This is interesting. I was browsing through the screencaps and noticed this poster on the wall in the Locke/Abbadon scene. "Get back in the game." That certainly could have a multitude of meanings in the scope of this story!

Poster on hospital wall (http://bp2.blogger.com/_Hxnvg45zlCw/SCPGxMfd8eI/AAAAAAAABFg/22ZgS7jPra4/s1600-h/pict+2008-05-08+10-28-2210.jpg)

While I think people often tend to over-think things that appear in the background of episodes this seems like something that was definitely deliberately chosen. I don't know about levels of meaning though, I think it's just reinforcing the message John is getting from the mystery guy.

I wonder how one gets OUT of the game? Dying on the island?